Despite the determined efforts of
some to paint MCS as a psychological disorder, there is no shortage of evidence
proving it to be a very real physical condition. For instance:
- Animal models point to a physical cause. Studies show that animals exposed to repeated low levels of chemicals over a period of time can become extremely reactive and sensitive to minute traces of those chemicals.
- People who became sick after exposure to certain
chemicals in Operation Desert Storm were found to have lower amounts of a
specific enzyme than others who had higher amounts and weren’t sickened.
- Women with a genetic profile involving two genes
associated with detoxifying toxic compounds were found to be over 18 times
more likely to have MCS compared to women with a different genetic makeup.
Women with variations in just one of the implicated genes were also more
likely to develop chemical sensitivities.
- Genetic abnormalities can themselves be caused
by chemicals. Many chemicals are capable of mutating genes or turning them
on or off.
- Lab tests of some MCS sufferers reveal abnormal
activity in one or more of the eight enzymes involved in heme production.
(Heme is the primary component of hemoglobin in red blood cells.)
- Nasal abnormalities consistent with chronic
inflammation have been found in patients with MCS. Damaged mucosa enhances
absorption of inhaled chemicals, and often permits rapid entry into the
brain.
- Testing often shows people with chemical
sensitivities to be “pathological detoxifiers” in which Phase I of liver
detoxification is faster than Phase II, leading to a buildup of toxic metabolites
in the body.
- Groups of independent researchers have found
distinct abnormalities of brain metabolism in people with MCS. The
neurotoxic pattern is very different from the abnormalities reported in
psychiatric disease.
- Tests measuring blood flow to the brain (SPECT
scans) show differences between MCS patients and normal controls. MCS
patients demonstrate severe deterioration when they are challenged by
chemicals in concentrations found in everyday situations.
Certain people may be more likely
than others to become chemically sensitive, but no one is immune to the danger.
We all have finite bodies capable of detoxifying a limited chemical burden, and
it's impossible to know who might be one exposure away from exceeding that
limit. Although it's wise to reduce and eliminate all chemical exposures, some
substances are especially likely to set people on the road to MCS. These are
known as "sensitizers."
Pesticides and formaldehyde (found in many personal care, cleaning,
building, and furniture products) are known sensitizers that are very important
to avoid.
People with chemical sensitivities
need your help to function in this world. Those without chemical sensitivities
need your help to stay that way. You, yourself, may be one chemical exposure away
from developing MCS. Reducing chemical exposures is the right thing to do for
everyone's sake.
http://www.environmentalhealth.ca/Ross2000.html